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1 July 1997 Monte Carlo modeling studies of the effect of physiological factors andother analytes on the determination of glucose concentration in vivoby near infrared optical absorption and scattering measurements
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Abstract
Determining the concentration of glucose in vivo by near-infrared spectroscopy is complicated by the effects of optical changes caused by fluctuations in temperature, tissue water content, and the concentration of other analytes. Mie theory and Monte Carlo computer simulation of light transport in optically absorbing and scattering media were used to investigate the magnitude of the changes in diffuse reflectance and transmittance from changes in glucose. Similarly, the possible interference in the glucose measurement from the other tissue parameters has been assessed and found to be significant.
Jianan Y. Qu and Brian C. Wilson "Monte Carlo modeling studies of the effect of physiological factors andother analytes on the determination of glucose concentration in vivoby near infrared optical absorption and scattering measurements," Journal of Biomedical Optics 2(3), (1 July 1997). https://doi.org/10.1117/12.275453
Published: 1 July 1997
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Cited by 45 scholarly publications and 14 patents.
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KEYWORDS
Glucose

Water

Tissues

Absorption

Tissue optics

Scattering

Refractive index

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