COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICAL SCIENCE AND CLINICS

Dispersion Effects in Partial Coherence Interferometry: Implications for Intraocular Ranging

[+] Author Affiliations
Christoph K. Hitzenberger, Angela Baumgartner, Wolfgang Drexler, Adolf F. Fercher

University of Vienna, Institute of Medical Physics, Wa¨hringer Strasse 13, A-1090?Vienna, Austria

J. Biomed. Opt. 4(1), 144-151 (Jan 01, 1999). doi:10.1117/1.429900
History: Received Nov. 7, 1997; Revised Nov. 10, 1998; Accepted Nov. 10, 1998
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Abstract

In nondispersive media, the minimum distance that can be resolved by partial coherence interferometry (PCI) and optical coherence tomography (OCT) is inversely proportional to the source spectral bandwidth. Dispersion tends to increase the signal width and to degrade the resolution. We analyze the situation for PCI ranging and OCT imaging of ocular structures. It can be shown that for each ocular segment an optimum source bandwidth yielding optimum resolution exists. If the resolution is to be improved beyond this point, the group dispersion of the ocular media has to be compensated. With the use of a dispersion compensating element, and employing a broadband superluminescent diode, we demonstrate a resolution of 5 μm in the retina of both a model eye and a human eye in vivo. This is an improvement by a factor of 2–3 as compared to currently used instruments. © 1999 Society of Photo-Optical Instrumentation Engineers.

© 1999 Society of Photo-Optical Instrumentation Engineers

Citation

Christoph K. Hitzenberger ; Angela Baumgartner ; Wolfgang Drexler and Adolf F. Fercher
"Dispersion Effects in Partial Coherence Interferometry: Implications for Intraocular Ranging", J. Biomed. Opt. 4(1), 144-151 (Jan 01, 1999). ; http://dx.doi.org/10.1117/1.429900


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