Research Papers

Noninvasive cerebral blood volume measurement during seizures using multichannel near infrared spectroscopic topography

[+] Author Affiliations
Eiju Watanabe

Tokyo Metropolitan Police Hospital, Department of Neurosurgery, 102 Tokyo, Japan

Atsushi Maki

Hitachi Central Research Laboratory

Fumio Kawaguchi

Hitachi Medical Corporation

Yuichi Yamashita, Hideaki Koizumi

Hitachi Central Research Laboratory

Yoshiaki Mayanagi

Tokyo Metropolitan Police Hospital, Department of Neurosurgery, 102 Tokyo, Japan

J. Biomed. Opt. 5(3), 287-290 (Jul 01, 2000). doi:10.1117/1.429998
History: Received Mar. 8, 1999; Revised June 25, 1999; Revised Oct. 19, 1999; Accepted Nov. 22, 1999
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Abstract

Near infrared spectroscopic topography (NIRS) is widely recognized as a noninvasive method to measure the regional cerebral blood volume (rCBV) dynamics coupled with neuronal activities. We analyzed the rCBV change in the early phase of epileptic seizures in 12 consecutive patients with medically intractable epilepsy. Seizure was induced by bemegride injection. We used eight-channel NIRS in nine cases and 24 channel in three cases. In all of the cases, rCBV increased rapidly after the seizure onset on the focus side. The increased rCBV was observed for about 30–60 s. The NIRS method can be applied to monitor the rCBV change continuously during seizures. Therefore, this method may be combined with ictal SPECT as one of the most reliable noninvasive methods of focus diagnosis. © 2000 Society of Photo-Optical Instrumentation Engineers.

© 2000 Society of Photo-Optical Instrumentation Engineers

Topics

Blood ; Near infrared

Citation

Eiju Watanabe ; Atsushi Maki ; Fumio Kawaguchi ; Yuichi Yamashita ; Hideaki Koizumi, et al.
"Noninvasive cerebral blood volume measurement during seizures using multichannel near infrared spectroscopic topography", J. Biomed. Opt. 5(3), 287-290 (Jul 01, 2000). ; http://dx.doi.org/10.1117/1.429998


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