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TECHNICAL PAPERS

Trans-abdominal monitoring of fetal arterial blood oxygenation using pulse oximetry

[+] Author Affiliations
Anna Zourabian, Andy Siegel

Tufts University, Electro-Optics and Bioengineering Department, Medford, Massachusetts?02155

Britton Chance, Nirmala Ramanujam

University of Pennsylvania, Department of Biochemistry and Biophysics, Philadelphia, Pennsylvania?19104

Martha Rode

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania?19104

David A. Boas

Tufts University, Electro-Optics and Bioengineering Department, Medford, Massachusetts?02155

Massachusetts General Hospital, Department of Radiology, NMR Center, Charlestown, Massachusetts?02129

J. Biomed. Opt. 5(4), 391-405 (Oct 01, 2000). doi:10.1117/1.1289359
History: Received Dec. 29, 1999; Revised Apr. 13, 2000; Accepted June 26, 2000
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Abstract

Pulse oximetry (oxygen saturation monitoring) has markedly improved medical care in many fields, including anesthesiology, intensive care, and newborn intensive care. In obstetrics, fetal heart rate monitoring remains the standard for intrapartum assessment of fetal well being. Fetal oxygen saturation monitoring is a new technique currently under development. It is potentially superior to electronic fetal heart rate monitoring (cardiotocography) because it allows direct assessment of both the fetal oxygen status and fetal tissue perfusion. Here we present the analysis for determining the most optimal wavelength selection for pulse oximetry. The wavelengths we chose as the most optimal are the first in the range of 670–720 nm and the second in the range of 825–925 nm. Further, we discuss the possible systematic errors during our measurements and their contribution to the obtained saturation results. We present feasibility studies for fetal pulse oximetry, monitored noninvasively through the maternal abdomen. Our preliminary experiments show that the fetal pulse can be discriminated from the maternal pulse and thus, in principle, the fetal arterial oxygen saturation can be obtained. We present the methodology for obtaining these data, and discuss the dependence of our measurements on the fetal position with respect to the optode assembly. © 2000 Society of Photo-Optical Instrumentation Engineers.

© 2000 Society of Photo-Optical Instrumentation Engineers

Topics

Abdomen ; Blood ; Oximetry

Citation

Anna Zourabian ; Andy Siegel ; Britton Chance ; Nirmala Ramanujam ; Martha Rode, et al.
"Trans-abdominal monitoring of fetal arterial blood oxygenation using pulse oximetry", J. Biomed. Opt. 5(4), 391-405 (Oct 01, 2000). ; http://dx.doi.org/10.1117/1.1289359


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