Research Papers

Determination of optical properties in semi-infinite turbid media using imaging measurements of frequency-domain photon migration obtained with an intensified charge-coupled device

[+] Author Affiliations
Michael Gurfinkel, Tianshu Pan

Texas A&M University, Photon Migration Laboratories, Department of Chemical Engineering, College Station, Texas?77843-3122

Eva M. Sevick-Muraca

Texas A&M University, Photon Migration Laboratories, Department of Chemical Engineering and Department of Chemistry, College Station, Texas?77843-3012 E-mail: eva-m-sevick@tamu.edu

J. Biomed. Opt. 9(6), 1336-1346 (Nov 01, 2004). doi:10.1117/1.1803549
History: Received Sep. 5, 2003; Revised Jan. 30, 2004; Revised Mar. 11, 2004; Accepted Mar. 16, 2004; Online November 22, 2004
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Frequency-domain photon migration measurements across the surface of a tissue-mimicking, semi-infinite phantom are acquired via an intensified charge-coupled device (ICCD) detection system and used in conjunction with the diffusion approximation to determine the optical properties. The absorption and reduced scattering coefficients are determined least accurately when relative measurements of average light intensity Idcrel are employed either alone or in a combination with relative modulation amplitude data Iacrel and/or relative phase shift data θrel. The absorption and reduced scattering coefficients are found accurate to within 15 and 11%, respectively, of the values obtained from standard single-pixel measurements when θrel measurements are employed alone or in combination with Iacrel data. © 2004 Society of Photo-Optical Instrumentation Engineers.

© 2004 Society of Photo-Optical Instrumentation Engineers

Citation

Michael Gurfinkel ; Tianshu Pan and Eva M. Sevick-Muraca
"Determination of optical properties in semi-infinite turbid media using imaging measurements of frequency-domain photon migration obtained with an intensified charge-coupled device", J. Biomed. Opt. 9(6), 1336-1346 (Nov 01, 2004). ; http://dx.doi.org/10.1117/1.1803549


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