Special Section on Optical Diagnostic Imaging from Bench to Bedside Instrumentation

Two-dimensional phased arrays of sources and detectors for depth discrimination in diffuse optical imaging

[+] Author Affiliations
Ning Liu, Angelo Sassaroli, Sergio Fantini

Tufts University, Department of Biomedical Engineering, Bioengineering Center, 4 Colby Street, Medford, Massachusetts 02155

J. Biomed. Opt. 10(5), 051801 (October 10, 2005). doi:10.1117/1.2085172
History: Received February 27, 2005; Revised April 07, 2005; Accepted April 08, 2005; Published October 10, 2005
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We present a multisource, multidetector phased-array approach to diffuse optical imaging that is based on postprocessing continuous-wave data. We previously showed that this approach enhances the spatial resolution of diffuse optical imaging. We now demonstrate the depth discrimination capabilities of this approach and its potential to perform tomographic sectioning of turbid media. The depth discrimination results from the dependence of the sensitivity function on the depth coordinate z. To demonstrate the potential of this approach, we perform an experimental study of a turbid medium containing cylindrical inhomogeneities that are placed 2.0, 3.0, and 4.0cm from a seven-element, 2-D source array. A single detector element is placed at a distance of 6.0 cm from the source array, and the measurement is repeated after switching the positions of the detector and the source array to simulate the case where both sources and detectors consist of a 2-D array of elements. We find that the proposed phased-array method is able to separate cylinders at different depths, thus showing cross-sectioning capabilities.

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© 2005 Society of Photo-Optical Instrumentation Engineers

Citation

Ning Liu ; Angelo Sassaroli and Sergio Fantini
"Two-dimensional phased arrays of sources and detectors for depth discrimination in diffuse optical imaging", J. Biomed. Opt. 10(5), 051801 (October 10, 2005). ; http://dx.doi.org/10.1117/1.2085172


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