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Research Papers

Interferometric measurements of dynamic changes of tear film

[+] Author Affiliations
Dorota H. Szczȩsna, Jarosław Jaroński, Henryk T. Kasprzak

Wroclaw University of Technology, Institute of Physics, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw, Poland

Ulf Stenevi

Sahlgren University Hospital, Department of Ophthalmology, S-431 80 Mölndal, Sweden

J. Biomed. Opt. 11(3), 034028 (June 07, 2006). doi:10.1117/1.2209881
History: Received December 01, 2005; Revised March 09, 2006; Accepted March 14, 2006; Published June 07, 2006
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Tear film stability plays an important role in the quality of vision. We present an interferometric method for assessing the stability of precorneal tear film in real time. A lateral shearing technique is applied as a noninvasive and sensitive method for investigating tear film stability and the smoothness of the tear film surface by quantitative evaluation of the interference fringe pattern. The evaporation of tears and the appearance of tear film break-up between blinks cause changes in the fringe geometry. For quantitative assessment of the fringe smoothness and consequently of the tear film structure, the fast Fourier transform (FFT) is applied. Four parameters are used to quantitatively estimate dynamic changes in the tear film stability of the cornea 20s after the eye blink. Examples of examined interferograms recorded in patients with healthy eyes, patients suffering from dry-eye syndrome, and patients wearing contact lenses are given. Significant differences between the stability of the tear film in the healthy eye and that in the dry eye and the eye with a contact lens are observed. The favorable influence of artificial tears applied in patients with dry-eye syndrome or contact lenses is also discussed.

© 2006 Society of Photo-Optical Instrumentation Engineers

Citation

Dorota H. Szczȩsna ; Jarosław Jaroński ; Henryk T. Kasprzak and Ulf Stenevi
"Interferometric measurements of dynamic changes of tear film", J. Biomed. Opt. 11(3), 034028 (June 07, 2006). ; http://dx.doi.org/10.1117/1.2209881


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