Research Papers

Feasibility of white-light time-resolved optical mammography

[+] Author Affiliations
Andrea Bassi, Lorenzo Spinelli, Cosimo D’Andrea, Arianna Giusto

ULTRAS-CNR-INFM and CNR-IFN, Politecnico di Milano, Dipartimento di Fisica, Piazza Leonardo da Vinci 32, 20133 Milano, Italy

Johannes Swartling

University of Cambridge, Department of Chemical Engineering, New Museums Site, Pembroke Street, Cambridge, CB2 3RA, United Kingdom

Antonio Pifferi, Alessandro Torricelli, Rinaldo Cubeddu

ULTRAS-CNR-INFM and CNR-IFN, Politecnico di Milano, Dipartimento di Fisica, Piazza Leonardo da Vinci 32, 20133 Milano, Italy

J. Biomed. Opt. 11(5), 054035 (October 03, 2006). doi:10.1117/1.2355663
History: Received April 12, 2006; Revised July 28, 2006; Accepted August 01, 2006; Published October 03, 2006; Online October 03, 2006
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We demonstrate the feasibility of white-light time-resolved optical mammography. The instrumentation is based on supercontinuum light generated in photonic crystal fiber and 32-channel parallel time-correlated single-photon-counting detection. Total measurement time is of the order of 10min for typical clinical applications. Preliminary measurements performed on volunteers show the ability of the system to determine tissue constituent concentrations and structure over the entire breast area. Furthermore, measurements on a tissue-like sample demonstrate detection and characterization of inclusions.

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© 2006 Society of Photo-Optical Instrumentation Engineers

Citation

Andrea Bassi ; Lorenzo Spinelli ; Cosimo D’Andrea ; Arianna Giusto ; Johannes Swartling, et al.
"Feasibility of white-light time-resolved optical mammography", J. Biomed. Opt. 11(5), 054035 (October 03, 2006). ; http://dx.doi.org/10.1117/1.2355663


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