Research Papers

Novel flexible light diffuser and irradiation properties for photodynamic therapy

[+] Author Affiliations
Baerbel Selm, Markus Rothmaier, Martin Camenzind

Empa, Swiss Federal Laboratories for Materials Testing and Research, Laboratory for Protection and Physiology, CH-9014 St. Gallen, Switzerland

Tania Khan, Heinrich Walt

University Hospital Zürich, Research Division of Gynecology, CH-8091 Zürich, Switzerland

J. Biomed. Opt. 12(3), 034024 (June 22, 2007). doi:10.1117/1.2749737
History: Received December 01, 2006; Revised February 21, 2007; Accepted February 22, 2007; Published June 22, 2007
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Many current light diffusers for photodynamic therapy are inflexible, and the applied light dose is difficult to adjust during treatment, especially on complex body surfaces. A thin and flexible luminous textile is developed using plastic optical fibers as a light distributor. The textile diffuser is evaluated for flexibility, irradiance, brightness distribution, and temperature rise with a 652-nm laser set to 100mW. The bending force of the textile diffuser resembles a defined optical film. On the textile surface, an average output power of 3.6±0.6mWcm2 is measured, corresponding to a transmission rate of 40±3.8% on an area of 11cm2. Aluminum backing enhances the irradiance to the face (treatment side). The measured brightness distribution seems to lie within a range similar to other photodynamic therapy (PDT) devices. A power setting of 100mW increases the temperature of the textile diffuser surface of up to 27°C, and 1W raises the temperature above 40°C. Results confirm that the flexible textile diffuser supplies suitable radiation for low fluence rate photodynamic therapy on an area of several cm2.

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© 2007 Society of Photo-Optical Instrumentation Engineers

Citation

Baerbel Selm ; Markus Rothmaier ; Martin Camenzind ; Tania Khan and Heinrich Walt
"Novel flexible light diffuser and irradiation properties for photodynamic therapy", J. Biomed. Opt. 12(3), 034024 (June 22, 2007). ; http://dx.doi.org/10.1117/1.2749737


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New design of textile light diffusers for photodynamic therapy. Mater Sci Eng C Mater Biol Appl 2013;33(3):1170-5.
A light blanket for intraoperative photodynamic therapy. Proc SPIE Int Soc Opt Eng 2013;7380():73801W.
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