Research Papers

Measurement of visco-elastic properties of breast-tissue mimicking materials using diffusing wave spectroscopy

[+] Author Affiliations
C. Usha Devi, R. Sreekumari Bharat Chandran, R. Mohan Vasu

Indian Institute of Science, Department of Instrumentation, Bangalore 560 012, India

Ajay K. Sood

Indian Institute of Science, Department of Physics, Bangalore 560 012, India

J. Biomed. Opt. 12(3), 034035 (May 25, 2007). doi:10.1117/1.2743081
History: Received August 06, 2006; Revised December 05, 2006; Accepted February 22, 2007; Published May 25, 2007
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Diffusing wave spectroscopy (DWS), without the use of tracer particles, has been used to study the internal dynamics of polyvinyl alcohol (PVA) phantoms, which mimic the properties of normal and malignant breast tissues. From the measured intensity autocorrelations, the mean square displacement (MSD) of phantom meshing is estimated, leading to the storage and loss moduli of the medium covering frequencies up to 10KHz. These are verified with independent measurements from a dynamic mechanical analyzer (DMA) at low frequencies. We thus prove the usefulness of DWS to extract visco-elastic properties of the phantom and its possible application in detecting malignancy in soft tissues.

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© 2007 Society of Photo-Optical Instrumentation Engineers

Citation

C. Usha Devi ; R. Sreekumari Bharat Chandran ; R. Mohan Vasu and Ajay K. Sood
"Measurement of visco-elastic properties of breast-tissue mimicking materials using diffusing wave spectroscopy", J. Biomed. Opt. 12(3), 034035 (May 25, 2007). ; http://dx.doi.org/10.1117/1.2743081


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