Research Papers

Phase retardation measurement of retinal nerve fiber layer by polarization-sensitive spectral-domain optical coherence tomography and scanning laser polarimetry

[+] Author Affiliations
Masahiro Yamanari

University of Tsukuba, Computational Optics Group, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan and Computational Optics and Ophthalmology Group, Tsukuba, Ibaraki 305-8573, Japan

Masahiro Miura

Tokyo Medical University, Department of Ophthalmology, 3-20-1 Chuo, Amimachi, Inashiki, Ibaraki, 300-0395 Japan and Computational Optics and Ophthalmology Group, Tsukuba, Ibaraki 305-8573, Japan

Shuichi Makita

University of Tsukuba, Computational Optics Group, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan and Computational Optics and Ophthalmology Group, Tsukuba, Ibaraki 305-8573, Japan

Toyohiko Yatagai

University of Tsukuba, Institute of Applied Physics, 1-1-1 Tennodai Tsukuba, Ibaraki 305-8573, Japan

Yoshiaki Yasuno

University of Tsukuba, Computational Optics Group, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan and Computational Optics and Ophthalmology Group, Tsukuba, Ibaraki 305-8573, Japan

J. Biomed. Opt. 13(1), 014013 (February 25, 2008). doi:10.1117/1.2841024
History: Received March 15, 2007; Revised October 01, 2007; Accepted October 24, 2007; Published February 25, 2008
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Phase retardation of in vivo human retinal nerve fiber layer (RNFL) is quantitatively measured by two methods—polarization-sensitive spectral-domain optical coherence tomography (PS-SD-OCT) and scanning laser polarimetry (SLP). An en face cumulative phase retardation map is calculated from the three-dimensional (3-D) phase retardation volume of healthy and glaucomatous eyes measured by PS-SD-OCT. It is shown that the phase retardation curves around the optic nerve head measured by PS-SD-OCT and SLP have similar values except near the retinal blood vessels. PS-SD-OCT can measure the cumulative phase retardation of RNFL as well as SLP, which will allow the evaluation of RNFL for glaucomatous eyes.

© 2008 Society of Photo-Optical Instrumentation Engineers

Citation

Masahiro Yamanari ; Masahiro Miura ; Shuichi Makita ; Toyohiko Yatagai and Yoshiaki Yasuno
"Phase retardation measurement of retinal nerve fiber layer by polarization-sensitive spectral-domain optical coherence tomography and scanning laser polarimetry", J. Biomed. Opt. 13(1), 014013 (February 25, 2008). ; http://dx.doi.org/10.1117/1.2841024


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