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Special Section on Optical Clearing of Tissues and Cells

Effect on blood glucose monitoring of skin pressure exerted by an optical coherence tomography probe

[+] Author Affiliations
Veronika V. Sapozhnikova, Roman V. Kuranov, Inga Cicenaite

The University of Texas Medical Branch, Center for Biomedical Engineering, Laboratory for Optical Sensing and Monitoring, Galveston, Texas 77555-0456

Rinat O. Esenaliev

The University of Texas Medical Branch, Center for Biomedical Engineering, Laboratory for Optical Sensing and Monitoringand Department of Neuroscience and Cell Biology and Department of Anesthesiology, Galveston, Texas 77555-0456

Donald S. Prough

The University of Texas Medical Branch, Department of Anesthesiology, Galveston, Texas 77555-0456

J. Biomed. Opt. 13(2), 021112 (July 13, 2007March 04, 2008March 05, 2008April 25, 2008). doi:10.1117/1.2909671
History: Received July 13, 2007; Revised March 04, 2008; Accepted March 05, 2008; Published April 25, 2008
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We proposed to use optical coherence tomography (OCT) for continuous noninvasive blood glucose monitoring, and recently we significantly improved the sensitivity of this technique. The accuracy of OCT glucose monitoring is limited by several factors, including variation of tissue pressure exerted by the OCT probe. We studied the influence of high (>10kPa) and low (<1kPa) pressure levels on OCT blood glucose monitoring. We showed that controlling external pressure to <1kPa substantially improved the accuracy and reproducibility of OCT-based glucose monitoring.

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© 2008 Society of Photo-Optical Instrumentation Engineers

Citation

Veronika V. Sapozhnikova ; Rinat O. Esenaliev ; Donald S. Prough ; Roman V. Kuranov and Inga Cicenaite
"Effect on blood glucose monitoring of skin pressure exerted by an optical coherence tomography probe", J. Biomed. Opt. 13(2), 021112 (July 13, 2007March 04, 2008March 05, 2008April 25, 2008). ; http://dx.doi.org/10.1117/1.2909671


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