Research Papers

Quasi-simultaneous optical coherence tomography and confocal imaging

[+] Author Affiliations
Irina Trifanov, Michael Hughes, Adrian Gh. Podoleanu

University of Kent, School of Physical Sciences, Applied Optics Group, Canterbury, CT2 7NH, United Kingdom

Richard B. Rosen

Advanced Retinal Imaging Center, New York Eye and Ear Infirmary, New York, New York 10003 and New York Medical College, Valhalla, New York 10595

J. Biomed. Opt. 13(4), 044015 (July 18, 2008). doi:10.1117/1.2957051
History: Received December 20, 2007; Revised March 11, 2008; Accepted March 11, 2008; Published July 18, 2008
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A new approach of acquiring quasi-simultaneous optical coherence tomography (OCT) and confocal images is presented. The two images are generated using different principles, OCT and confocal microscopy. When the system is used to image the retina, the two images have depth resolutions, at present, of <20μm and 1mm, respectively. The acquisition and display of en face OCT and confocal images are quasi-simultaneous, without the need of a beamsplitter. By using a chopper to periodically obstruct the reference beam in the OCT interferometer, synchronized with the XY-transversal scanner, much higher acquisition speed is obtained than in a previous report where we flipped an opaque screen in the reference arm of the interferometer. Successful operation of the novel configuration was achieved by: (1) stable synchronization of the chopper’s movement with the horizontal line scanner and (2) fast self-adjusting of the gain value of avalanche photodiodes, depending on the optical power. Images from coin, leaves, and retina in vivo have been collected to demonstrate the functionality of the system.

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© 2008 Society of Photo-Optical Instrumentation Engineers

Citation

Irina Trifanov ; Michael Hughes ; Adrian Gh. Podoleanu and Richard B. Rosen
"Quasi-simultaneous optical coherence tomography and confocal imaging", J. Biomed. Opt. 13(4), 044015 (July 18, 2008). ; http://dx.doi.org/10.1117/1.2957051


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