Research Papers

Real-time optical monitoring of radio-frequency tissue fusion by continuous wave transmission spectroscopy

[+] Author Affiliations
Timmy Floume, Richard R. A. Syms

Imperial College, Electrical and Electronic Engineering Department Optical and Semiconductor Device Group, Exhibition Road, London, SW7 2BT

Ara W. Darzi, George B. Hanna

Imperial College, St. Mary's Hospital, Biosurgery and Surgical Technology Department, South Wharf Road, London, NW2 1NY

J. Biomed. Opt. 13(6), 064006 (November 10, 2008). doi:10.1117/1.3006062
History: Received May 07, 2008; Revised August 26, 2008; Accepted August 26, 2008; Published November 10, 2008
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Radio-frequency (RF) tissue fusion is a novel method of tissue approximation that can seal tissue without the need for sutures or staples, based on the combined effects of heat and pressure on the apposed tissue surfaces. RF delivery must be controlled and optimized to obtain a reproducible, reliable seal. We use real-time optical measurements to improve understanding of the tissue modifications induced by RF fusion. The main macroscopic transformations are thermal denaturation and dehydration. Light propagation in tissue is a function of both and therefore should provide interesting insight into the dynamic of occurring phenomena. Quantification by continuous wave technique has proven challenging. We proposed an algorithm based on the measurement of the absolute transmittance of the tissue, making use of the modified Beer-Lambert law. The experimental method and the data algorithm are demonstrated by RF fusion of porcine small bowel. The proposed optical measurement modality is well adapted to modern surgical instrumentation used for minimally invasive procedures.

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© 2008 Society of Photo-Optical Instrumentation Engineers

Citation

Timmy Floume ; Richard R. A. Syms ; Ara W. Darzi and George B. Hanna
"Real-time optical monitoring of radio-frequency tissue fusion by continuous wave transmission spectroscopy", J. Biomed. Opt. 13(6), 064006 (November 10, 2008). ; http://dx.doi.org/10.1117/1.3006062


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