Research Papers

Image reconstruction method for a two-layer tissue structure accounts for chest-wall effects in breast imaging

[+] Author Affiliations
Chen Xu

University of Connecticut, Department of Electrical and Computer Engineering, Storrs, Connecticut 06269

Mini Das

University of Massachusetts Medical School, Department of Radiology, Worcester, Massachusetts 01655

Yasaman Ardeshirpour, Quing Zhu

University of Connecticut, Department of Electrical and Computer Engineering, Storrs, Connecticut 06269

J. Biomed. Opt. 13(6), 064029 (January 05, 2009). doi:10.1117/1.3041497
History: Received July 15, 2008; Revised October 15, 2008; Accepted October 16, 2008; Published January 05, 2009
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We develop a new tomographic imaging reconstruction algorithm for a two-layer tissue structure. Simulations and phantom experiments show more accurate reconstruction of target optical properties compared with those results obtained from a semi-infinite tissue model for layered structures. This improvement is mainly attributed to the more accurate estimation of background optical properties and more accurate estimation of weight matrix for imaging reconstruction by considering the light propagation effect in the second layer. Clinical results of breast lesions are also presented to demonstrate the utility of this new imaging algorithm.

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© 2008 Society of Photo-Optical Instrumentation Engineers

Citation

Chen Xu ; Mini Das ; Yasaman Ardeshirpour and Quing Zhu
"Image reconstruction method for a two-layer tissue structure accounts for chest-wall effects in breast imaging", J. Biomed. Opt. 13(6), 064029 (January 05, 2009). ; http://dx.doi.org/10.1117/1.3041497


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