Research Papers

Ellipsometric surface plasmon resonance

[+] Author Affiliations
Wei-Liang Hsu

National Taiwan University, Institute of Applied Mechanics, Number 1, Section 4, Roosevelt Road, Taipei 10617, Taiwan

Shu-Sheng Lee

National Taiwan Ocean University, Department of Systems Engineering and Naval Architecture, Number 2, Pei-Ning Road, Keelung 20224, Taiwan

Chih-Kung Lee

National Taiwan University, Institute of Applied Mechanics and Department of Engineering Science and Ocean Engineering, Number 1, Section 4, Roosevelt Road, Taipei 10617, Taiwan and Industrial Technology Research Institute, Number 195, Section 4, Chung Hsing Road, Chu-Tung, Hsinchu 31040, Taiwan

J. Biomed. Opt. 14(2), 024036 (April 13, 2009). doi:10.1117/1.3116713
History: Received July 08, 2008; Revised February 10, 2009; Accepted February 11, 2009; Published April 13, 2009
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We develop a new multifunctional optical biochip system that integrates an ellipsometer with a surface plasmon resonance (SPR) feature. This newly developed biochip biosensor, which we call ESPR for an ellipsometric SPR, provides us with a system to retrieve detailed information such as the optical properties of immobilized biomolecular monolayers, surface concentration variations of biomedical reactions, and kinetic affinity between biomolecules required for further biotech analysis. Our ESPR can also serve as both a research and development tool and a manufacturing tool for various biomedical applications.

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© 2009 Society of Photo-Optical Instrumentation Engineers

Citation

Wei-Liang Hsu ; Shu-Sheng Lee and Chih-Kung Lee
"Ellipsometric surface plasmon resonance", J. Biomed. Opt. 14(2), 024036 (April 13, 2009). ; http://dx.doi.org/10.1117/1.3116713


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