Research Papers

Characterizing liquid turbid media by frequency-domain photon-migration spectroscopy

[+] Author Affiliations
Biju Cletus, Rainer Künnemeyer

The University of Waikato, Hillcrest Road, Hamilton, Waikato 3210, New Zealand

Paul Martinsen, Andrew McGlone, Robert Jordan

The New Zealand Institute of Plant and Food Research, Limited, East Street, Hamilton, Waikato 3214, New Zealand

J. Biomed. Opt. 14(2), 024041 (April 28, 2009). doi:10.1117/1.3119282
History: Received December 17, 2008; Revised February 16, 2009; Accepted February 16, 2009; Published April 28, 2009
Text Size: A A A

We present a wavelength-tunable frequency-domain instrument for the characterization of liquid turbid media. The instrument employs a tunable titanium-sapphire laser modulated by an acousto-optic modulator. The absorption and reduced scattering coefficient of Intralipid® 20%, diluted to concentrations of 0.94 to 4.00%, are measured over the wavelength range 710to850nm at 10-nm intervals. The standard measurement errors for the absorption and reduced scattering coefficients are 1 and 2.5%, respectively. Extrapolation to 0% Intralipid® concentration gives an absorption coefficient that closely follows that of water, overestimating the absorption of pure water by less than 10%. The reduced scattering coefficient is compared at 750nm with published results and is found consistent within the experimental error. We compare the reduced scattering coefficient to an estimate based on Mie theory and find the reduced scattering coefficient underestimated the Mie theory result by about 9%.

Figures in this Article
© 2009 Society of Photo-Optical Instrumentation Engineers

Citation

Biju Cletus ; Rainer Künnemeyer ; Paul Martinsen ; Andrew McGlone and Robert Jordan
"Characterizing liquid turbid media by frequency-domain photon-migration spectroscopy", J. Biomed. Opt. 14(2), 024041 (April 28, 2009). ; http://dx.doi.org/10.1117/1.3119282


Tables

Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

PubMed Articles
Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.