Research Papers

Single-walled carbon nanotubes as a multimodal-thermoacoustic and photoacoustic-contrast agent

[+] Author Affiliations
Manojit Pramanik

Washington University in St. Louis, Department of Biomedical Engineering, Optical Imaging Laboratory, Campus Box 1097, 1 Brookings Drive, St. Louis, Missouri 63130

Magdalena Swierczewska, Danielle Green, Balaji Sitharaman

Stony Brook University, 348 Psychology A Building Biomedical Engineering, Stony Brook, New York 11794

Lihong V. Wang

Washington University in St. Louis, Department of Biomedical Engineering, Optical Imaging Laboratory, Campus Box 1097, 1 Brookings Drive, St. Louis, Missouri 63130

J. Biomed. Opt. 14(3), 034018 (June 08, 2009). doi:10.1117/1.3147407
History: Received February 13, 2009; Revised March 22, 2009; Accepted March 26, 2009; Published June 08, 2009
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We have developed a novel carbon nanotube-based contrast agent for both thermoacoustic and photoacoustic tomography. In comparison to deionized water, single-walled carbon nanotubes exhibited more than twofold signal enhancement for thermoacoustic tomography at 3GHz. In comparison to blood, they exhibited more than sixfold signal enhancement for photoacoustic tomography at 1064nm wavelength. The large contrast enhancement of single-walled carbon nanotubes was further corroborated by tissue phantom imaging studies.

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© 2009 Society of Photo-Optical Instrumentation Engineers

Citation

Manojit Pramanik ; Magdalena Swierczewska ; Danielle Green ; Balaji Sitharaman and Lihong V. Wang
"Single-walled carbon nanotubes as a multimodal-thermoacoustic and photoacoustic-contrast agent", J. Biomed. Opt. 14(3), 034018 (June 08, 2009). ; http://dx.doi.org/10.1117/1.3147407


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