Research Papers

Feasibility study of autofluorescence mammary ductoscopy

[+] Author Affiliations
Alexandre Douplik

Ontario Cancer Institute, University Health Network, 7-417 610 University Avenue, Toronto, M5G 2M9 Canada and Xillix Ltd., 620 University Avenue, Toronto, Ontario M5G 2C1 Canada and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen Graduate School in Advanced Optical Technologies, Paul-Gordan-Straße 6, Erlangen, 91052, Germany

Wey L. Leong, Alexandra M. Easson

University Health Network, Princess Margaret Hospital, Department of Surgical Oncology, 610 University Avenue, Suite 3-130, Toronto, M5G 2M9 Canada and Ontario Cancer Institute, University Health Network, 7-417 610 University Avenue, Toronto, M5G 2M9 Canada

Susan Done, George Netchev

Ontario Cancer Institute, University Health Network, 7-417 610 University Avenue, Toronto, M5G 2M Canada

Brian C. Wilson

Ontario Cancer Institute, University Health Network, 7-417 610 University Avenue, Toronto, M5G 2M9 Canada and University of Toronto, Department of Medical Biophysics, Ontario Cancer Institute, Princess Margaret Hospital, 610 University Avenue, Room 7-411, Toronto, M5G 2M9 Canada

J. Biomed. Opt. 14(4), 044036 (August 25, 2009). doi:10.1117/1.3210773
History: Received April 09, 2009; Revised June 25, 2009; Accepted June 26, 2009; Published August 25, 2009
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We report the technical feasibility of autofluorescence ductoscopy in the ex-vivo setting. The current imaging algorithm for visualizing tumor tissue against the normal tissue background, although developed and optimized for other organs, appears to provide discrimination between intraductal tumor and normal ductal tissue. Point fluoroscopy is also performed. Although the optical “geometry” for this is different, the findings are consistent with the imaging observations.

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© 2009 Society of Photo-Optical Instrumentation Engineers

Citation

Alexandre Douplik ; Wey L. Leong ; Alexandra M. Easson ; Susan Done ; George Netchev, et al.
"Feasibility study of autofluorescence mammary ductoscopy", J. Biomed. Opt. 14(4), 044036 (August 25, 2009). ; http://dx.doi.org/10.1117/1.3210773


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