Research Papers

Design considerations for surface plasmon resonance-based fiber-optic detection of human blood group

[+] Author Affiliations
Anuj K. Sharma

Friedrich-Schiller University, Institute of Physical Chemistry, 10 Lessingstrasse, Jena, 07743, Germany

Rajan Jha

Carrer de la Coruna, 13 Mediterranean Technology Park, Castelldefels, Barcelona 08860, Spain

Himansu S. Pattanaik

University of Central Florida, College of Optics and Photonics (CREOL), Orlando, Florida 32816

Gerhard J. Mohr

Friedrich-Schiller University, Institute of Physical Chemistry, 10 Lessingstrasse, Jena 07743 Germany

J. Biomed. Opt. 14(6), 064041 (December 28, 2009). doi:10.1117/1.3275476
History: Received April 26, 2009; Revised October 05, 2009; Accepted October 22, 2009; Published December 28, 2009; Online December 28, 2009
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A fiber-optic surface plasmon resonance (SPR) sensor for the detection of human blood groups is proposed. Previous experimental results describing the wavelength-dependent refractive index variation of multiple samples of different blood groups are considered for theoretical calculations. The spectral interrogation method, along with silica fiber and silver layer, is considered. The sensor’s performance is closely analyzed in terms of shift in SPR wavelength and SPR curve width in order to optimize the design parameters for a reliable and accurate blood-group identifier. The sensor design parameters include silver layer thickness, fiber core diameter, sensing region length, and temperature variation. The results are explained in terms of light coupling and plasmon resonance condition. The proposed sensing probe is able to provide high sensitivity and accuracy of blood-group detection, thereby opening an easy and reliable window for medical applications.

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© 2009 Society of Photo-Optical Instrumentation Engineers

Citation

Anuj K. Sharma ; Rajan Jha ; Himansu S. Pattanaik and Gerhard J. Mohr
"Design considerations for surface plasmon resonance-based fiber-optic detection of human blood group", J. Biomed. Opt. 14(6), 064041 (December 28, 2009). ; http://dx.doi.org/10.1117/1.3275476


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