Special Section on Optical Methods in Vascular Biology and Medicine

Laser speckle contrast imaging in biomedical optics

[+] Author Affiliations
David A. Boas

Harvard Medical School, Massachusetts General Hospital, Anthinoula A. Martinos Center for Biomedical Imaging, 149 13th Street, Charlestown, Massachusetts 02129

Andrew K. Dunn

The University of Texas at Austin, Department of Biomedical Engineering, 1 University Station, C0800, Austin, Texas 78712

J. Biomed. Opt. 15(1), 011109 (January 13, 2010). doi:10.1117/1.3285504
History: Received June 08, 2009; Revised July 20, 2009; Accepted July 29, 2009; Published January 13, 2010; Online January 13, 2010
Text Size: A A A

First introduced in the 1980s, laser speckle contrast imaging is a powerful tool for full-field imaging of blood flow. Recently laser speckle contrast imaging has gained increased attention, in part due to its rapid adoption for blood flow studies in the brain. We review the underlying physics of speckle contrast imaging and discuss recent developments to improve the quantitative accuracy of blood flow measures. We also review applications of laser speckle contrast imaging in neuroscience, dermatology and ophthalmology.

Figures in this Article
© 2010 Society of Photo-Optical Instrumentation Engineers


Blood ; Speckle ; Brain ; Lasers


David A. Boas and Andrew K. Dunn
"Laser speckle contrast imaging in biomedical optics", J. Biomed. Opt. 15(1), 011109 (January 13, 2010). ; http://dx.doi.org/10.1117/1.3285504

Access This Article
Sign In to Access Full Content
Please Wait... Processing your request... Please Wait.
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Your Session has timed out. Please sign back in to continue.
Sign In to Access Full Content


Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

PubMed Articles

Buy this article ($18 for members, $25 for non-members).
Sign In