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Special Section on Optical Methods in Vascular Biology and Medicine

Laser speckle contrast imaging in biomedical optics

[+] Author Affiliations
David A. Boas

Harvard Medical School, Massachusetts General Hospital, Anthinoula A. Martinos Center for Biomedical Imaging, 149 13th Street, Charlestown, Massachusetts 02129

Andrew K. Dunn

The University of Texas at Austin, Department of Biomedical Engineering, 1 University Station, C0800, Austin, Texas 78712

J. Biomed. Opt. 15(1), 011109 (January 13, 2010). doi:10.1117/1.3285504
History: Received June 08, 2009; Revised July 20, 2009; Accepted July 29, 2009; Published January 13, 2010; Online January 13, 2010
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First introduced in the 1980s, laser speckle contrast imaging is a powerful tool for full-field imaging of blood flow. Recently laser speckle contrast imaging has gained increased attention, in part due to its rapid adoption for blood flow studies in the brain. We review the underlying physics of speckle contrast imaging and discuss recent developments to improve the quantitative accuracy of blood flow measures. We also review applications of laser speckle contrast imaging in neuroscience, dermatology and ophthalmology.

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© 2010 Society of Photo-Optical Instrumentation Engineers

Topics

Blood ; Speckle ; Brain ; Lasers

Citation

David A. Boas and Andrew K. Dunn
"Laser speckle contrast imaging in biomedical optics", J. Biomed. Opt. 15(1), 011109 (January 13, 2010). ; http://dx.doi.org/10.1117/1.3285504


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