Research Papers: General

Epidermal laser stimulation of action potentials in the frog sciatic nerve

[+] Author Affiliations
Nichole M. Jindra

Air Force Research Laboratory, 2624 Louis Bauer Drive, Brooks City-Base, Texas 78235

Douglas Goddard, Michelle Imholte

Northrop Grumman, 4241 Woodcock Drive, Suite B-100, San Antonio, Texas 78228-1330

Robert J. Thomas

Air Force Research Laboratory, 2624 Louis Bauer Drive, Brooks City-Base, Texas 78235

J. Biomed. Opt. 15(1), 015002 (February 04, 2010). doi:10.1117/1.3292014
History: Received April 02, 2008; Revised September 15, 2009; Accepted November 24, 2009; Published February 04, 2010; Online February 04, 2010
Text Size: A A A

Measurements of laser-stimulated action potentials in the sciatic nerve of leopard frogs (Rana pipiens) are made using two infrared lasers. The dorsal sides of the frog’s hind limbs are exposed to short-pulsed 1540- and 1064-nm wavelengths at three separate spot sizes: 2, 3, and 4mm. Energy density thresholds are determined for eliciting an action potential at each experimental condition. Results from these exposures show similar evoked potential thresholds for both wavelengths. The 2-mm-diam spot sizes yield action potentials at radiant exposure levels almost double that seen with larger beam sizes.

Figures in this Article
© 2010 Society of Photo-Optical Instrumentation Engineers

Topics

Lasers ; Nerve ; Skin

Citation

Nichole M. Jindra ; Douglas Goddard ; Michelle Imholte and Robert J. Thomas
"Epidermal laser stimulation of action potentials in the frog sciatic nerve", J. Biomed. Opt. 15(1), 015002 (February 04, 2010). ; http://dx.doi.org/10.1117/1.3292014


Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

PubMed Articles
Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.