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Research Papers: Imaging

Real-time diffuse optical tomography based on structured illumination

[+] Author Affiliations
Samuel Bélanger, Maxime Abran

École Polytechnique de Montréal, Département de Génie Électrique and Institut de Génie Biomédical, C.P. 6079 Succ. Centre-Ville, Montréal, Québec H3C 3A7, Canada

Xavier Intes

Rensselaer Polytechnic Institute, Department of Biomedical Engineering, 110 8th Street, Troy, New York 12180-3590

Christian Casanova

Université de Montréal, École d’Optométrie, Laboratoire des Neurosciences de la Vision, CP 6128 Succ. Centre-Ville, Québec, H3C 3J7, Canada

Frédéric Lesage

École Polytechnique de Montréal, Département de Génie Électrique and Institut de Génie Biomédical, C.P. 6079 Succ. Centre-Ville, Montréal, Québec H3C 3A7, Canada

J. Biomed. Opt. 15(1), 016006 (July 29, 2009November 04, 2009November 11, 2009January 15, 2010January 15, 2010). doi:10.1117/1.3290818
History: Received July 29, 2009; Revised November 04, 2009; Accepted November 11, 2009; Published January 15, 2010; Online January 15, 2010
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A new optical acquisition scheme based on a pair of digital micromirror devices is developed and applied to three-dimensional tomographic imaging of turbid media. By using pairs of illumination-detection patterns with a single detector, we were able to perform high-resolution quantitative volumetric imaging of absorption heterogeneities embedded in optically thick samples. Additionally, a tomographic reconstruction algorithm was implemented on a graphical processor unit to provide optical reconstructions at a frame rate of 2Hz. The structured illumination method proposed in this work has significant cost advantages over camera systems, as only a single detector is required. This configuration also has the potential to increase frame rate.

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© 2010 Society of Photo-Optical Instrumentation Engineers

Citation

Samuel Bélanger ; Xavier Intes ; Christian Casanova ; Frédéric Lesage and Maxime Abran
"Real-time diffuse optical tomography based on structured illumination", J. Biomed. Opt. 15(1), 016006 (July 29, 2009November 04, 2009November 11, 2009January 15, 2010January 15, 2010). ; http://dx.doi.org/10.1117/1.3290818


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