Special Section on Photons Plus Ultrasound: Imaging and Sensing

Real-time optoacoustic monitoring and three-dimensional mapping of a human arm vasculature

[+] Author Affiliations
Matthew P. Fronheiser

Seno Medical Instruments, 3838 Medical Drive, San Antonio, Texas 78229

Sergey A. Ermilov, Hans-Peter Brecht, Andre Conjusteau, Richard Su, Ketan Mehta, Alexander A. Oraevsky

Fairway Medical Technologies, 710 North Post Oak Road, Houston, Texas 77024

J. Biomed. Opt. 15(2), 021305 (April 02, 2010). doi:10.1117/1.3370336
History: Received August 27, 2009; Revised November 04, 2009; Accepted November 05, 2009; Published April 02, 2010; Online April 02, 2010
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We present our findings from a real-time laser optoacoustic imaging system (LOIS). The system utilizes a Q-switched Nd:YAG laser; a standard 128-channel ultrasonic linear array probe; custom electronics and custom software to collect, process, and display optoacoustic (OA) images at 10Hz. We propose that this system be used during preoperative mapping of forearm vessels for hemodialysis treatment. To demonstrate the real-time imaging capabilities of the system, we show OA images of forearm vessels in a volunteer and compare our results to ultrasound images of the same region. Our OA images show blood vessels in high contrast. Manipulations with the probe enable us to locate and track arteries and veins of a forearm in real time. We also demonstrate the ability to combine a series of OA image slices into a volume for spatial representation of the vascular network. Finally, we use frame-by-frame analysis of the recorded OA video to measure dynamic changes of the crossection of the ulnar artery.

Figures in this Article
Brilliant B, Big Sky Laser/Quantel, Bozeman, Montana

Citation

Matthew P. Fronheiser ; Sergey A. Ermilov ; Hans-Peter Brecht ; Andre Conjusteau ; Richard Su, et al.
"Real-time optoacoustic monitoring and three-dimensional mapping of a human arm vasculature", J. Biomed. Opt. 15(2), 021305 (April 02, 2010). ; http://dx.doi.org/10.1117/1.3370336


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