Research Papers: Imaging

Near-infrared imaging of the sinuses: preliminary evaluation of a new technology for diagnosing maxillary sinusitis

[+] Author Affiliations
Usama Mahmood, Albert Cerussi, Reza Dehdari, Quoc Nguyen, Timothy Kelley, Bruce Tromberg, Brian Wong

University of California at Irvine, Department of Biomedical Engineering and Department of Otolaryngology—Head and Neck Surgery, Beckman Laser Institute, 1002 Health Sciences Road, Irvine, California 92612

J. Biomed. Opt. 15(3), 036011 (May 26, 2010). doi:10.1117/1.3431718
History: Received August 31, 2009; Revised March 31, 2010; Accepted April 04, 2010; Published May 26, 2010; Online May 26, 2010
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Diagnosing sinusitis remains a challenge for primary care physicians. There is a need for a simple, office-based technique to aid in the diagnosis of sinusitis without the cost and radiation risk of conventional radiologic imaging. We designed a low-cost near-infrared (NIR) device to transilluminate the maxillary sinuses. The use of NIR light allows for greater interrogation of deep-tissue structures as compared to visible light. NIR imaging of 21 patients was performed and compared with computed tomography (CT) scans. Individual maxillary sinuses were scored on a scale from 0 to 2 based on their degree of aeration present on CT and similarly based on the NIR signal penetration into the maxilla on NIR images. Our results showed that air-filled and fluid/tissue–filled spaces can be reasonably distinguished by their differing NIR signal penetration patterns, with average NIR imaging scores for fluid-filled maxillary sinuses (0.93±0.78, n=29) significantly lower than those for normal maxillary sinuses (1.62±0.57, n=13) (p=0.003). NIR imaging of the sinuses is a simple, safe, and cost-effective modality that can potentially aid in the diagnosis of sinusitis. Long-term, significant device refinement and large clinical trials will be needed to determine the diagnostic accuracy of this technique.

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© 2010 Society of Photo-Optical Instrumentation Engineers

Topics

Near infrared

Citation

Usama Mahmood ; Albert Cerussi ; Reza Dehdari ; Quoc Nguyen ; Timothy Kelley, et al.
"Near-infrared imaging of the sinuses: preliminary evaluation of a new technology for diagnosing maxillary sinusitis", J. Biomed. Opt. 15(3), 036011 (May 26, 2010). ; http://dx.doi.org/10.1117/1.3431718


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