Research Papers: Imaging

Absolute blood velocity measured with a modified fundus camera

[+] Author Affiliations
Donald D. Duncan

Portland State University, Department of Electrical and Computer Engineering, 1900 Southwest Fourth Avenue, Portland, Oregon 97201

Paul Lemaillet

The Catholic University of America, Department of Biomedical Engineering, 620 Michigan Avenue, Washington, DC 20064

Mohamed Ibrahim, Quan Dong Nguyen

Johns Hopkins University, Wilmer Eye Institute, 600 North Wolfe Street, Baltimore, Maryland 21287

Matthias Hiller

Portland State University, Department of Electrical and Computer Engineering, 1900 Southwest Fourth Avenue, Portland, Oregon 97201

Jessica Ramella-Roman

The Catholic University of America, Department of Biomedical Engineering, 620 Michigan Avenue, Washington, DC 20064 and Johns Hopkins University, School of Medicine, 600 North Wolfe Street, Baltimore, Maryland 21287

J. Biomed. Opt. 15(5), 056014 (October 06, 2010). doi:10.1117/1.3494565
History: Received May 01, 2010; Revised August 02, 2010; Accepted August 19, 2010; Published October 06, 2010; Online October 06, 2010
Text Size: A A A

We present a new method for the quantitative estimation of blood flow velocity, based on the use of the Radon transform. The specific application is for measurement of blood flow velocity in the retina. Our modified fundus camera uses illumination from a green LED and captures imagery with a high-speed CCD camera. The basic theory is presented, and typical results are shown for an in vitro flow model using blood in a capillary tube. Subsequently, representative results are shown for representative fundus imagery. This approach provides absolute velocity and flow direction along the vessel centerline or any lateral displacement therefrom. We also provide an error analysis allowing estimation of confidence intervals for the estimated velocity.

© 2010 Society of Photo-Optical Instrumentation Engineers

Citation

Donald D. Duncan ; Paul Lemaillet ; Mohamed Ibrahim ; Quan Dong Nguyen ; Matthias Hiller, et al.
"Absolute blood velocity measured with a modified fundus camera", J. Biomed. Opt. 15(5), 056014 (October 06, 2010). ; http://dx.doi.org/10.1117/1.3494565


Tables

Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

PubMed Articles
Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.