Review Papers

Optical coherence elastography: current status and future applications

[+] Author Affiliations
Cuiru Sun, Beau Standish

Ryerson University, Department of Electrical and Computer Engineering, Biophotonics and Bioengineering Laboratory, Toronto, Ontario M5B 2K3, Canada

Victor X. D. Yang

Ryerson University, Department of Electrical and Computer Engineering, Biophotonics and Bioengineering Laboratory, Toronto, Ontario M5B 2K3, Canada

University of Toronto, Division of Neurosurgery, Toronto, Ontario M5G 1L2, Canada

J. Biomed. Opt. 16(4), 043001 (April 01, 2011). doi:10.1117/1.3560294
History: Received July 21, 2010; Revised January 10, 2011; Accepted February 07, 2011; Published April 01, 2011; Online April 01, 2011
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Optical coherence tomography (OCT) has several advantages over other imaging modalities, such as angiography and ultrasound, due to its inherently high in vivo resolution, which allows for the identification of morphological tissue structures. Optical coherence elastography (OCE) benefits from the superior spatial resolution of OCT and has promising applications, including cancer diagnosis and the detailed characterization of arterial wall biomechanics, both of which are based on the elastic properties of the tissue under investigation. We present OCE principles based on techniques associated with static and dynamic tissue excitation, and their corresponding elastogram image-reconstruction algorithms are reviewed. OCE techniques, including the development of intravascular- or catheter-based OCE, are in their early stages of development but show great promise for surgical oncology or intravascular cardiology applications.

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© 2011 Society of Photo-Optical Instrumentation Engineers (SPIE)

Citation

Cuiru Sun ; Beau Standish and Victor X. D. Yang
"Optical coherence elastography: current status and future applications", J. Biomed. Opt. 16(4), 043001 (April 01, 2011). ; http://dx.doi.org/10.1117/1.3560294


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