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Research Papers: Imaging

Integrated ultrasound and photoacoustic probe for co-registered intravascular imaging

[+] Author Affiliations
Wei Wei

Wuhan University, Department of Physics and Key Laboratory of Acoustic and Photonic Materials and Devices, Ministry of Education, Wuhan 430072, China

University of California, Irvine, Beckman Laser Institute and Medical Clinic, Department of Biomedical Engineering, Irvine, California 92612–1475

Xiang Li, Qifa Zhou, K. Kirk Shung

University of Southern California, NIH Transducer Resource Center and Department of Biomedical Engineering, California 90089

Zhongping Chen

University of California, Irvine, Beckman Laser Institute and Medical Clinic, Department of Biomedical Engineering, Irvine, California 92612–1475

J. Biomed. Opt. 16(10), 106001 (October 03, 2011). doi:10.1117/1.3631798
History: Received March 28, 2011; Revised August 07, 2011; Accepted August 09, 2011; Published October 03, 2011; Online October 03, 2011
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We report on the synergy of an integrated ultrasound (US) and photoacoustic (PA) probe system for intravascular imaging. The combined dual-modality probe is based on a 39 MHz ring-shaped US transducer which detects both US echoes and laser-generated PA signals. By combining optical fiber, US transducer, and micromirror, we can obtain intravascular cross-sectional B-scan images by internal illumination of the sample. The performance of the probe is evaluated in a phantom study. Moreover, the coaxially designed probe also provides co-registered US and PA images of a normal rabbit aorta, which demonstrates the imaging ability of the dual-functional system, implying future clinical applications.

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© 2011 Society of Photo-Optical Instrumentation Engineers (SPIE)

Citation

Wei Wei ; Xiang Li ; Qifa Zhou ; K. Kirk Shung and Zhongping Chen
"Integrated ultrasound and photoacoustic probe for co-registered intravascular imaging", J. Biomed. Opt. 16(10), 106001 (October 03, 2011). ; http://dx.doi.org/10.1117/1.3631798


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