Research Papers: Imaging

Terahertz pulsed imaging in vivo: measurements and processing methods

[+] Author Affiliations
Edward P. J. Parrott, Stanley M. Y. Sy, Thierry Blu

Chinese University of Hong Kong, Department of Electronic Engineering, Shatin, Hong Kong

Vincent P. Wallace

University of Western Australia, School of Physics, Perth, WA 6009, Australia

Emma Pickwell-MacPherson

The Hong Kong University of Science & Technology, Electronic and Computer Engineering, Clearwater Bay, Hong Kong

J. Biomed. Opt. 16(10), 106010 (October 03, 2011). doi:10.1117/1.3642002
History: Received June 24, 2011; Revised August 31, 2011; Accepted September 01, 2011; Published October 03, 2011; Online October 03, 2011
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This paper presents a number of data processing algorithms developed to improve the accuracy of results derived from datasets acquired by a recently designed terahertz handheld probe. These techniques include a baseline subtraction algorithm and a number of algorithms to extract the sample impulse response: double Gaussian inverse filtering, frequency-wavelet domain deconvolution, and sparse deconvolution. In vivo measurements of human skin are used as examples, and a comparison is made of the terahertz impulse response from a number of different skin positions. The algorithms presented enables both the spectroscopic and time domain properties of samples measured in reflection geometry to be better determined compared to previous calculation methods.

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© 2011 Society of Photo-Optical Instrumentation Engineers (SPIE)

Citation

Edward P. J. Parrott ; Stanley M. Y. Sy ; Thierry Blu ; Vincent P. Wallace and Emma Pickwell-MacPherson
"Terahertz pulsed imaging in vivo: measurements and processing methods", J. Biomed. Opt. 16(10), 106010 (October 03, 2011). ; http://dx.doi.org/10.1117/1.3642002


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