Research Papers: Therapeutic

Porcine cortical bone ablation by ultrashort pulsed laser irradiation

[+] Author Affiliations
Brent Emigh, Joseph E. Hayward

McMaster University, Department of Medical Physics and Applied Radiation Sciences, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4K1

Ran An, Eugene M. Hsu, Travis H. R. Crawford

McMaster University, Department of Engineering Physics, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4K1

Harold K. Haugen

McMaster University, Department of Engineering Physics, and Department of Physics and Astronomy, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4K1

Gregory R. Wohl

McMaster University, Department of Mechanical Engineering, and School of Biomedical Engineering, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4K1

Qiyin Fang

McMaster University, Department of Engineering Physics, and School of Biomedical Engineering, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4K1

J. Biomed. Opt. 17(2), 028001 (Feb 27, 2012). doi:10.1117/1.JBO.17.2.028001
History: Received September 3, 2011; Revised December 15, 2011; Accepted December 19, 2011
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Abstract.  Ultrashort pulsed lasers in bone ablation show promise for many orthopedic applications. To minimize collateral tissue damage and control the ablation process, the ablation threshold fluence must be well characterized. Using an amplified femtosecond laser (170 fs, 800 nm, 1 kHz), the ablation threshold on unaltered porcine cortical bone was measured using the D2 method at multiple incident pulse numbers ranging from 25 to 1000 pulses per spot. The lowered threshold at greater pulse numbers indicated an incubation effect. Using a power law model, the incubation coefficient of unaltered porcine cortical bone was found to be 0.89±0.03. Through extrapolation, the single-pulse ablation threshold was found to be 3.29±0.14J/cm2.

Figures in this Article
© 2012 Society of Photo-Optical Instrumentation Engineers

Topics

Bone ; Lasers ; Tissues

Citation

Brent Emigh ; Ran An ; Eugene M. Hsu ; Travis H. R. Crawford ; Harold K. Haugen, et al.
"Porcine cortical bone ablation by ultrashort pulsed laser irradiation", J. Biomed. Opt. 17(2), 028001 (Feb 27, 2012). ; http://dx.doi.org/10.1117/1.JBO.17.2.028001


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