Design strategies for high-sensitivity refractive index sensors based on the principle of wavelength-selective resonant coupling in dual-core photonic crystal fibers are presented. Phase matching at a single wavelength can be achieved between an analyte-filled microstructured core and a small core with a down-doped rod or one small air hole in the center, thus enabling selectively directional resonant-coupling between the two cores. The transmission spectra of the output light presents a notch at the index-matched wavelength, yielding a resonant wavelength depending on the refractive index of the analyte. Numerical simulations demonstrate that both of the two proposed sensors can be used for highly sensitive detection of low-index analyte. In particular, the configuration realized by introducing the fiber with a small air hole in one core can be used to the detection of the analyte index around 1.33 and the sensitivity reach to per refractive index unit (RIU). In addition, the detection limit is as low as at .