Special Section on Photoacoustic Imaging and Sensing

Photoacoustic computed tomography correcting for heterogeneity and attenuation

[+] Author Affiliations
Chao Huang, Liming Nie, Robert W. Schoonover, Lihong V. Wang, Mark A. Anastasio

Washington University in St. Louis, Department of Biomedical Engineering, St. Louis, Missouri 63130

J. Biomed. Opt. 17(6), 061211 (May 07, 2012). doi:10.1117/1.JBO.17.6.061211
History: Received October 18, 2011; Revised January 20, 2012; Accepted January 20, 2012
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Abstract.  We report an investigation of image reconstruction in photoacoustic tomography for objects that possess heterogeneous material and acoustic attenuation distributions. When the object contains materials, such as bone and soft-tissue, that are modeled using power law attenuation models with distinct exponents, we demonstrate that the effects of acoustic attenuation due to the most strongly attenuating material can be compensated for if the attenuation of the other less attenuating material(s) are neglected. Experiments with phantom objects are presented to validated our findings.

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© 2012 Society of Photo-Optical Instrumentation Engineers

Citation

Chao Huang ; Liming Nie ; Robert W. Schoonover ; Lihong V. Wang and Mark A. Anastasio
"Photoacoustic computed tomography correcting for heterogeneity and attenuation", J. Biomed. Opt. 17(6), 061211 (May 07, 2012). ; http://dx.doi.org/10.1117/1.JBO.17.6.061211


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