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Research Papers

Accuracy of cornea and lens biometry using anterior segment optical coherence tomography

[+] Author Affiliations
Mark C. M. Dunne, Leon N. Davies, James S. Wolffsohn

Aston University, Ophthalmic Research Group, Birmingham, United Kingdom

J. Biomed. Opt. 12(6), 064023 (June 15, 2007August 21, 2007August 22, 2007December 18, 2007). doi:10.1117/1.2821844
History: Received June 15, 2007; Revised August 21, 2007; Accepted August 22, 2007; Published December 18, 2007
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We assess the accuracy of the Visante anterior segment optical coherence tomographer (AS-OCT) and present improved formulas for measurement of surface curvature and axial separation. Measurements are made in physical model eyes. Accuracy is compared for measurements of corneal thickness (d1) and anterior chamber depth (d2) using-built-in AS-OCT software versus the improved scheme. The improved scheme enables measurements of lens thickness (d3) and surface curvature, in the form of conic sections specified by vertex radii and conic constants. These parameters are converted to surface coordinates for error analysis. The built-in AS-OCT software typically overestimates [mean±standarddeviation(SD)]d1 by +62±4μm and d2 by +4±88μm. The improved scheme reduces d1(0.4±4μm) and d2(0±49μm) errors while also reducing d3 errors from +218±90 (uncorrected) to +14±123μm (corrected). Surface x coordinate errors gradually increase toward the periphery. Considering the central 6mm zone of each surface, the x coordinate errors for anterior and posterior corneal surfaces reached +3±10 and 0±23μm, respectively, with the improved scheme. Those of the anterior and posterior lens surfaces reached +2±22 and +11±71μm, respectively. Our improved scheme reduced AS-OCT errors and could, therefore, enhance pre- and postoperative assessments of keratorefractive or cataract surgery, including measurement of accommodating intraocular lenses.

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© 2007 Society of Photo-Optical Instrumentation Engineers

Citation

Mark C. M. Dunne ; Leon N. Davies and James S. Wolffsohn
"Accuracy of cornea and lens biometry using anterior segment optical coherence tomography", J. Biomed. Opt. 12(6), 064023 (June 15, 2007August 21, 2007August 22, 2007December 18, 2007). ; http://dx.doi.org/10.1117/1.2821844


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