Research Papers: Sensing

Gold nanoisland structures integrated in a lab-on-a-chip for plasmonic detection of bovine growth hormone

[+] Author Affiliations
Jayan Ozhikandathil, Simona Badilescu, Muthukumaran Packirisamy

Concordia University, Optical Bio-Microsystems Laboratory, Department of Mechanical and Industrial Engineering, Montreal, H3G 1M8, Canada

J. Biomed. Opt. 17(7), 077001 (Jul 05, 2012). doi:10.1117/1.JBO.17.7.077001
History: Received October 18, 2011; Revised February 21, 2012; Accepted February 22, 2012
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Abstract.  Three-dimensional gold nanostructures fabricated through a novel convective assembly method are treated thermally to obtain a nanoisland morphology. The new structure is proved to be adequate for the detection of bovine growth hormone, by using an immunoassay method based on the localized surface plasmon resonance band of gold. The nanoisland structures are integrated into a microfluidic device and the spectral measurements are carried out by introducing the device directly in the light beam of a ultraviolet-visible spectrophotometer. The principal motivation for this work is the need for a simple and rapid method of detection of hormone levels in milk and milk products.

© 2012 Society of Photo-Optical Instrumentation Engineers

Citation

Jayan Ozhikandathil ; Simona Badilescu and Muthukumaran Packirisamy
"Gold nanoisland structures integrated in a lab-on-a-chip for plasmonic detection of bovine growth hormone", J. Biomed. Opt. 17(7), 077001 (Jul 05, 2012). ; http://dx.doi.org/10.1117/1.JBO.17.7.077001


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