JBO Letters

Localized thermal mapping using coherent anti-Stokes Raman spectroscopy

[+] Author Affiliations
Hope T. Beier, Benjamin A. Rockwell

Air Force Research Laboratory, 4141 Petroleum Road, Building 3260 Fort Sam Houston, Texas 78234

Gary D. Noojin

TASC, Inc., 4141 Petroleum Road, Building 3260, Fort Sam Houston, Texas 78234

J. Biomed. Opt. 17(8), 080501 (Jul 10, 2012). doi:10.1117/1.JBO.17.8.080501
History: Received May 2, 2012; Revised June 21, 2012; Accepted June 21, 2012
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Abstract.  Coherent anti-Stokes Raman scattering (CARS) spectroscopy is explored as a tool for obtaining micro-scale thermal measurements. A single femtosecond oscillator is used to pump a photonic crystal fiber to provide the broadband Stokes pulse. The CARS signals from the broad OH-stretching modes between 3000 and 3600cm1 are shown to correlate with temperature with an accuracy of ±1°C for water and ±1.5°C for phosphate-buffered saline. Local variation of temperature is mapped on a microscopic level, using black-dyed microspheres as thermal sources.

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© 2012 Society of Photo-Optical Instrumentation Engineers

Citation

Hope T. Beier ; Gary D. Noojin and Benjamin A. Rockwell
"Localized thermal mapping using coherent anti-Stokes Raman spectroscopy", J. Biomed. Opt. 17(8), 080501 (Jul 10, 2012). ; http://dx.doi.org/10.1117/1.JBO.17.8.080501


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