Research Papers: Imaging

Feasibility of in vivo intravascular photoacoustic imaging using integrated ultrasound and photoacoustic imaging catheter

[+] Author Affiliations
Andrei B. Karpiouk, Bo Wang, Stanislav Y. Emelianov

University of Texas at Austin, Department of Biomedical Engineering, Austin, Texas 78712

James Amirian, Richard W. Smalling

University of Texas Health Science Center, Division of Cardiology, Houston, Texas 77030

J. Biomed. Opt. 17(9), 096008 (Sep 06, 2012). doi:10.1117/1.JBO.17.9.096008
History: Received September 30, 2011; Revised July 13, 2012; Accepted July 31, 2012
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Abstract.  Pilot studies of in vivo combined intravascular ultrasound (IVUS) and intravascular photoacoustic (IVPA) imaging are reported. A recently introduced prototype of an integrated IVUS/IVPA imaging catheter consisting of a single-element ultrasound transducer and a light delivery system based on a single optical fiber was adapted and used for in vivo imaging of a coronary stent deployed in a rabbit’s thoracic aorta in the presence of luminal blood. The results suggest that in vivo IVUS/IVPA imaging is feasible using the integrated IVUS/IVPA imaging catheter. The challenges of in vivo combined IVUS/IVPA imaging are discussed, and further improvements on the design of the catheter and the clinical imaging system are proposed.

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© 2012 Society of Photo-Optical Instrumentation Engineers

Citation

Andrei B. Karpiouk ; Bo Wang ; James Amirian ; Richard W. Smalling and Stanislav Y. Emelianov
"Feasibility of in vivo intravascular photoacoustic imaging using integrated ultrasound and photoacoustic imaging catheter", J. Biomed. Opt. 17(9), 096008 (Sep 06, 2012). ; http://dx.doi.org/10.1117/1.JBO.17.9.096008


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