Research Papers: Imaging

Intravascular optical coherence tomography to characterize tissue deformation during angioplasty: preliminary experiments with artery phantoms

[+] Author Affiliations
Hamed Azarnoush

Institut des Matériaux Industriels, Conseil National de Recherches Canada, 75 de Mortagne, Boucherville, Quebec J4B 6Y4, Canada

McGill University, Centre for Intelligent Machines, 3480 University, Montreal, Quebec, H3A 2A7, Canada

Montreal Neurological Hospital and Institute, 3801 University, Montreal, Quebec H3A 2B4, Canada

Sébastien Vergnole

Institut des Matériaux Industriels, Conseil National de Recherches Canada, 75 de Mortagne, Boucherville, Quebec J4B 6Y4, Canada

Horiba Scientific, 231 rue de Lille, 59650 Villeneuve d’Ascq, France

Valérie Pazos, Charles-Étienne Bisaillon, Guy Lamouche

Institut des Matériaux Industriels, Conseil National de Recherches Canada, 75 de Mortagne, Boucherville, Quebec J4B 6Y4, Canada

Benoit Boulet

McGill University, Centre for Intelligent Machines, 3480 University, Montreal, Quebec, H3A 2A7, Canada

J. Biomed. Opt. 17(9), 096015 (Sep 18, 2012). doi:10.1117/1.JBO.17.9.096015
History: Received January 24, 2012; Revised July 22, 2012; Accepted August 17, 2012
Text Size: A A A

Abstract.  We explored the potential of intravascular optical coherence tomography (IVOCT) to assess deformation during angioplasty balloon inflation. Using a semi-compliant balloon and artery phantoms, we considered two experimental scenarios. The goal for the first scenario was to investigate if variation in the elasticity of the structure surrounding the balloon could be sensed by IVOCT monitoring. In this scenario, we used three single-layer phantoms with various mechanical properties. Image analysis was performed to extract the inner and outer diameters of the phantoms at various pressures. The goal for the second scenario was twofold. First, we investigated the IVOCT capability to monitor a more complex balloon inflation process. The balloon was in a folded state prior to inflation. This allowed studying two stages of deformation: during balloon unfolding and during balloon expansion. Second, we investigated IVOCT capability to monitor the deformation in a three-layer phantom used to better mimic a true artery. So, not only were the IVOCT images processed to provide the inner and outer diameters of the phantom, but the layer thicknesses were also determined. In both scenarios, IVOCT monitoring revealed to be very efficient in providing relevant information about the phantom deformation during balloon inflation.

Figures in this Article
© 2012 Society of Photo-Optical Instrumentation Engineers

Citation

Hamed Azarnoush ; Sébastien Vergnole ; Valérie Pazos ; Charles-Étienne Bisaillon ; Benoit Boulet, et al.
"Intravascular optical coherence tomography to characterize tissue deformation during angioplasty: preliminary experiments with artery phantoms", J. Biomed. Opt. 17(9), 096015 (Sep 18, 2012). ; http://dx.doi.org/10.1117/1.JBO.17.9.096015


Tables

Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

PubMed Articles
Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.