Research Papers: Imaging

Minimal residual method provides optimal regularization parameter for diffuse optical tomography

[+] Author Affiliations
Ravi Prasad K. Jagannath, Phaneendra K. Yalavarthy

Indian Institute of Science, Supercomputer Education and Research Centre, Bangalore 560012, India

J. Biomed. Opt. 17(10), 106015 (Oct 10, 2012). doi:10.1117/1.JBO.17.10.106015
History: Received July 16, 2012; Revised September 11, 2012; Accepted September 19, 2012
Text Size: A A A

Abstract.  The inverse problem in the diffuse optical tomography is known to be nonlinear, ill-posed, and sometimes under-determined, requiring regularization to obtain meaningful results, with Tikhonov-type regularization being the most popular one. The choice of this regularization parameter dictates the reconstructed optical image quality and is typically chosen empirically or based on prior experience. An automated method for optimal selection of regularization parameter that is based on regularized minimal residual method (MRM) is proposed and is compared with the traditional generalized cross-validation method. The results obtained using numerical and gelatin phantom data indicate that the MRM-based method is capable of providing the optimal regularization parameter.

Figures in this Article
© 2012 Society of Photo-Optical Instrumentation Engineers

Citation

Ravi Prasad K. Jagannath and Phaneendra K. Yalavarthy
"Minimal residual method provides optimal regularization parameter for diffuse optical tomography", J. Biomed. Opt. 17(10), 106015 (Oct 10, 2012). ; http://dx.doi.org/10.1117/1.JBO.17.10.106015


Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.