Research Papers: Imaging

Automatic retinal vessel segmentation based on active contours method in Doppler spectral-domain optical coherence tomography

[+] Author Affiliations
Wenzhong Liu, Tan Liu, Ji Yi

Northwestern University, Department of Biomedical Engineering, 2145 Sheridan Road, Evanston, Illinois 60208

Wei Song

Northwestern University, Department of Biomedical Engineering, 2145 Sheridan Road, Evanston, Illinois 60208

Harbin Institute of Technology, Department of Physics, 92 West Da-Zhi Street Nangang District, Harbin, Heilongjiang 150080, China

Hao F. Zhang

Northwestern University, Department of Biomedical Engineering, 2145 Sheridan Road, Evanston, Illinois 60208

Northwestern University, Feinberg School of Medicine, Department of Ophthalmology, 45 North Michigan Avenue, Suite 440, Chicago, Illinois 60611

J. Biomed. Opt. 18(1), 016002 (Jan 04, 2013). doi:10.1117/1.JBO.18.1.016002
History: Received October 23, 2012; Revised November 25, 2012; Accepted November 28, 2012
Text Size: A A A

Abstract.  We achieved fast and automatic retinal vessel segmentation by employing the active contours method in Doppler spectral-domain optical coherence tomography (SD-OCT). In a typical OCT B-scan image, we first extracted the phase variations between adjacent A-lines and removed bulk motion. Then we set the initial contour as the boundary of the whole image and iterated until all of the segmented vessel contours became stabilized. Using a typical office computer, the whole segmentation took no more than 50 s, making real-time retinal vessel segmentation possible. We tested the active contours method segmentation in both controlled phantom and in vivo rodent eye images.

Figures in this Article
© 2013 Society of Photo-Optical Instrumentation Engineers

Citation

Wenzhong Liu ; Tan Liu ; Wei Song ; Ji Yi and Hao F. Zhang
"Automatic retinal vessel segmentation based on active contours method in Doppler spectral-domain optical coherence tomography", J. Biomed. Opt. 18(1), 016002 (Jan 04, 2013). ; http://dx.doi.org/10.1117/1.JBO.18.1.016002


Tables

Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

PubMed Articles
Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.