Special Section on Optical Methods of Imaging in the Skin

Optical methods for noninvasive determination of carotenoids in human and animal skin

[+] Author Affiliations
Maxim E. Darvin, Martina C. Meinke, Wolfram Sterry, Juergen Lademann

Charité: Universitätsmedizin Berlin, Department of Dermatology, Venerology and Allergology, Center of Experimental and Applied Cutaneous Physiology (CCP), Charitéplatz 1, 10117 Berlin, Germany

J. Biomed. Opt. 18(6), 061230 (Feb 20, 2013). doi:10.1117/1.JBO.18.6.061230
History: Received September 26, 2012; Revised January 30, 2013; Accepted February 5, 2013
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Abstract.  Carotenoids are important substances for human skin due to their powerful antioxidant properties in reaction of neutralization of free radicals and especially reactive oxygen species, including singlet oxygen. Concentration of carotenoids in the skin could mirror the current redox status of the skin and should be investigated in vivo. Optical methods are ideally suited for determination of carotenoids in mammalian skin in vivo as they are both noninvasive and quick. Four different optical methods could be used for in vivo measurement of carotenoids in the human or animal skin: (1) resonance Raman spectroscopy; (2) Raman microscopy; (3) reflection spectroscopy; (4) skin color measurements. The advantages, shortcomings, and limitations of the above-mentioned optical methods are discussed.

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© 2013 Society of Photo-Optical Instrumentation Engineers

Topics

Skin

Citation

Maxim E. Darvin ; Martina C. Meinke ; Wolfram Sterry and Juergen Lademann
"Optical methods for noninvasive determination of carotenoids in human and animal skin", J. Biomed. Opt. 18(6), 061230 (Feb 20, 2013). ; http://dx.doi.org/10.1117/1.JBO.18.6.061230


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