Research Papers: General

Modeling of the temporal effects of heating during infrared neural stimulation

[+] Author Affiliations
Alexander C. Thompson, Scott A. Wade, Peter J. Cadusch, William G. A. Brown, Paul R. Stoddart

Swinburne University of Technology, Faculty of Engineering and Industrial Sciences, PO Box 218, Hawthorn 3122, Australia

J. Biomed. Opt. 18(3), 035004 (Mar 07, 2013). doi:10.1117/1.JBO.18.3.035004
History: Received September 14, 2012; Revised January 14, 2013; Accepted February 18, 2013
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Abstract.  A model of infrared neural stimulation (INS) has been developed to allow the temporal characteristics of different stimulation parameters and geometries to be better understood. The model uses a finite element approach to solve the heat equation and allow detailed analysis of heat during INS with both microsecond and millisecond laser pulses. When compared with experimental data, the model provides insight into the mechanisms behind INS. In particular, the analysis suggests that there may be two broad regimes of INS: the process tends to be limited by the total pulse energy for pulse lengths below 100 μs, while the temperature gradient with respect to time becomes more important above 100 μs.

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© 2013 Society of Photo-Optical Instrumentation Engineers

Citation

Alexander C. Thompson ; Scott A. Wade ; Peter J. Cadusch ; William G. A. Brown and Paul R. Stoddart
"Modeling of the temporal effects of heating during infrared neural stimulation", J. Biomed. Opt. 18(3), 035004 (Mar 07, 2013). ; http://dx.doi.org/10.1117/1.JBO.18.3.035004


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