Research Papers: Imaging

Acoustic attenuation compensation in photoacoustic tomography using time-variant filtering

[+] Author Affiliations
Bradley E. Treeby

University College London, Department of Medical Physics and Bioengineering, Gower Street, London WC1E 6BT, United Kingdom

J. Biomed. Opt. 18(3), 036008 (Mar 14, 2013). doi:10.1117/1.JBO.18.3.036008
History: Received January 21, 2013; Revised February 19, 2013; Accepted February 20, 2013
Text Size: A A A

Abstract.  Most reconstruction algorithms used in photoacoustic tomography do not account for the effects of acoustic attenuation on the recorded signals. For experimental measurements made in biological tissue, the frequency dependent acoustic attenuation causes high frequency components of the propagating photoacoustic waves to be significantly reduced. This signal loss manifests as a depth dependent magnitude error and blurring of features within the reconstructed image. Here, a general method for compensating for this attenuation using time-variant filtering is presented. The time-variant filter is constructed to correct for acoustic attenuation and dispersion following a frequency power law under the assumption the distribution of attenuation parameters is homogeneous. The filter is then applied directly to the recorded time-domain signals using a form of nonstationary convolution. Regularization is achieved using a time-variant window where the cutoff frequency is based on the local time-frequency distribution of the recorded signals. The approach is computationally efficient and can be used in combination with any detector geometry or reconstruction algorithm. Numerical and experimental examples are presented to illustrate the utility of the technique. Clear improvements in the magnitude and resolution of reconstructed photoacoustic images are seen when acoustic attenuation compensation is applied.

Figures in this Article
© 2013 Society of Photo-Optical Instrumentation Engineers

Citation

Bradley E. Treeby
"Acoustic attenuation compensation in photoacoustic tomography using time-variant filtering", J. Biomed. Opt. 18(3), 036008 (Mar 14, 2013). ; http://dx.doi.org/10.1117/1.JBO.18.3.036008


Tables

Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement

 

 

  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.