Special Section on Optical Imaging, Sensing, and Light Interactions in Cells and Tissues

Dependence of light scattering profile in tissue on blood vessel diameter and distribution: a computer simulation study

[+] Author Affiliations
Hamootal Duadi, Dror Fixler, Rachela Popovtzer

Bar-Ilan University, Institute of Nanotechnology and Advanced Materials, Faculty of Engineering, Ramat-Gan 52900, Israel

J. Biomed. Opt. 18(11), 111408 (Jul 25, 2013). doi:10.1117/1.JBO.18.11.111408
History: Received April 11, 2013; Revised June 19, 2013; Accepted June 28, 2013
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Abstract.  Most methods for measuring light–tissue interactions focus on the volume reflectance while very few measure the transmission. We investigate both diffusion reflection and diffuse transmission at all exit angles to receive the full scattering profile. We also investigate the influence of blood vessel diameter on the scattering profile of a circular tissue. The photon propagation path at a wavelength of 850 nm is calculated from the absorption and scattering constants via Monte Carlo simulation. Several simulations are performed where a different vessel diameter and location were chosen but the blood volume was kept constant. The fraction of photons exiting the tissue at several central angles is presented for each vessel diameter. The main result is that there is a central angle that below which the photon transmission decreased for lower vessel diameters while above this angle the opposite occurred. We find this central angle to be 135 deg for a two-dimensional 10-mm diameter circular tissue cross-section containing blood vessels. These findings can be useful for monitoring blood perfusion and oxygen delivery in the ear lobe and pinched tissues.

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© 2013 Society of Photo-Optical Instrumentation Engineers

Citation

Hamootal Duadi ; Dror Fixler and Rachela Popovtzer
"Dependence of light scattering profile in tissue on blood vessel diameter and distribution: a computer simulation study", J. Biomed. Opt. 18(11), 111408 (Jul 25, 2013). ; http://dx.doi.org/10.1117/1.JBO.18.11.111408


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