Special Section on Optical Imaging, Sensing, and Light Interactions in Cells and Tissues

Photoinduced cell morphology alterations quantified within adipose tissues by spectral optical coherence tomography

[+] Author Affiliations
Irina Yu. Yanina

Saratov State University, Research-Educational Institute of Optics and Biophotonics, 83 Astrakhanskaya Street, Saratov 410012, Russia

Saratov State Medical University, Department of Medical and Biological Physics, 112 B. Kazachia Street, Saratov 410026, Russia

Natalia A. Trunina

Saratov State University, Research-Educational Institute of Optics and Biophotonics, 83 Astrakhanskaya Street, Saratov 410012, Russia

Valery V. Tuchin

Saratov State University, Research-Educational Institute of Optics and Biophotonics, 83 Astrakhanskaya Street, Saratov 410012, Russia

Laboratory of Laser Diagnostics of Technical and Living Systems of Precise Mechanics and Control Institute of the Russian Academy of Sciences, 24 Rabochaya, Saratov 410028, Russia

University of Oulu, Optoelectronics and Measurement Techniques Laboratory, P.O. Box 4500, Oulu, 90014 Finland

J. Biomed. Opt. 18(11), 111407 (Aug 02, 2013). doi:10.1117/1.JBO.18.11.111407
History: Received May 4, 2013; Revised June 25, 2013; Accepted June 28, 2013
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Abstract.  Morphological changes of the adipose tissue at phototreatment are studied in vitro using optical coherence tomography. The 200 to 600 μm fat tissue slices are used in the experiments. The observed change in the tissue structure was associated with fat cell lipolysis and destruction caused by the photodynamic effect. It is found that overall heating of a sample from room to physiological temperature leads to deeper and faster morphology tissue changes if other processing conditions are kept constant. These data support the hypothesis that photodynamic/photothermal treatment induces fat cell lipolysis during some period after treatment.

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© 2013 Society of Photo-Optical Instrumentation Engineers

Citation

Irina Yu. Yanina ; Natalia A. Trunina and Valery V. Tuchin
"Photoinduced cell morphology alterations quantified within adipose tissues by spectral optical coherence tomography", J. Biomed. Opt. 18(11), 111407 (Aug 02, 2013). ; http://dx.doi.org/10.1117/1.JBO.18.11.111407


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