JBO Letters

Optical resolution photoacoustic microendoscopy with ultrasound-guided insertion and array system detection

[+] Author Affiliations
Parsin Hajireza, Tyler Harrison, Alexander Forbrich, Roger Zemp

University of Alberta, Department of Electrical and Computer Engineering, Edmonton, Alberta T6G 2V4, Canada

J. Biomed. Opt. 18(9), 090502 (Sep 25, 2013). doi:10.1117/1.JBO.18.9.090502
History: Received June 27, 2013; Revised August 21, 2013; Accepted August 26, 2013
Text Size: A A A

Abstract.  Using a 0.8-mm-diameter image guide fiber bundle consisting of 30,000 single-mode fibers and an external linear array transducer, we demonstrate a dual-mode photoacoustic system capable of ultrasound-guided microendoscope insertion and photoacoustic imaging. The array optical resolution photoacoustic microendoscopy (AOR-PAME) system is designed to visualize the placement of the distal end of an endoscopy probe several centimeters into tissue, transmit scanning focused laser pulses into tissues via the fiber bundle, and acquire the generated photoacoustic signals. A ytterbium-doped fiber laser is tightly focused and is scanned across the proximal tip of the image guide fiber bundle using a two-dimensional galvanometer scanning mirror system. The end of the fiber bundle is used in contact mode with the object. The capabilities of AOR-PAME are demonstrated by imaging carbon fiber networks embedded in tissue-mimicking phantoms and the ears of a 60-g rat. The lateral resolution and signal-to-noise ratio are measured as 9 μm and 40 dB, respectively.

Figures in this Article
© 2013 Society of Photo-Optical Instrumentation Engineers

Citation

Parsin Hajireza ; Tyler Harrison ; Alexander Forbrich and Roger Zemp
"Optical resolution photoacoustic microendoscopy with ultrasound-guided insertion and array system detection", J. Biomed. Opt. 18(9), 090502 (Sep 25, 2013). ; http://dx.doi.org/10.1117/1.JBO.18.9.090502


Tables

Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement


 

  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.