Special Section on Optical Elastography and Measurement of Tissue Biomechanics

Tracking mechanical wave propagation within tissue using phase-sensitive optical coherence tomography: motion artifact and its compensation

[+] Author Affiliations
Shaozhen Song

University of Washington, Department of Bioengineering, 3720 15th Avenue NE, Seattle, Washington 98195

University of Dundee, School of Engineering, Physics and Mathematics, Dundee DD1 4HN, Scotland, United Kingdom

Zhihong Huang

University of Washington, Department of Bioengineering, 3720 15th Avenue NE, Seattle, Washington 98195

Ruikang K. Wang

University of Washington, Department of Bioengineering, 3720 15th Avenue NE, Seattle, Washington 98195

University of Washington, Department of Ophthalmology, 325 9th Avenue, Seattle, Washington 98104

J. Biomed. Opt. 18(12), 121505 (Oct 22, 2013). doi:10.1117/1.JBO.18.12.121505
History: Received June 25, 2013; Revised September 24, 2013; Accepted September 25, 2013
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Abstract.  We describe theoretical and experimental investigations of motion artifacts that can arise in the detection of shear wave propagating within tissue with phase-sensitive optical coherence tomography. We find that the motion artifact is a combined product of sample surface motion and refractive index difference between sample and air, which cannot be neglected when estimating the tissue motion within tissue. A method of compensating the motion artifact is demonstrated, the results of which emphasize the need for surface motion compensation when measuring the mechanical response for elastography or other biomedical applications.

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© 2013 Society of Photo-Optical Instrumentation Engineers

Citation

Shaozhen Song ; Zhihong Huang and Ruikang K. Wang
"Tracking mechanical wave propagation within tissue using phase-sensitive optical coherence tomography: motion artifact and its compensation", J. Biomed. Opt. 18(12), 121505 (Oct 22, 2013). ; http://dx.doi.org/10.1117/1.JBO.18.12.121505


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