Research Papers: Sensing

Study of dynamic pressure-induced refractive index change using derivative total reflection method

[+] Author Affiliations
Jin Wang, Qing Ye, Zhichao Deng, Tengqian Sun, Wenyuan Zhou, Jianchun Mei, Chunping Zhang, Jianguo Tian

Nankai University, School of Physics and TEDA Applied Physics School, MOE, Key Laboratory of Weak-Light Nonlinear Photonics, Tianjin 300071, China

J. Biomed. Opt. 18(11), 117005 (Nov 08, 2013). doi:10.1117/1.JBO.18.11.117005
History: Received June 13, 2013; Revised August 31, 2013; Accepted October 1, 2013
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Abstract.  We report the dynamic refractive index (RI) change of tissue under a stepped compression load using a custom-built pressure apparatus. Angle-dependent reflectance profiles of biotissue samples are recorded, and the RI values are resolved using the derivative total reflection method. These results are relevant for understanding the mechanism of mechanical optical clearing, for investigating tissue dynamics under mechanical stimuli, and for other biomedical applications.

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© 2013 Society of Photo-Optical Instrumentation Engineers

Citation

Jin Wang ; Qing Ye ; Zhichao Deng ; Tengqian Sun ; Wenyuan Zhou, et al.
"Study of dynamic pressure-induced refractive index change using derivative total reflection method", J. Biomed. Opt. 18(11), 117005 (Nov 08, 2013). ; http://dx.doi.org/10.1117/1.JBO.18.11.117005


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