Research Papers: Imaging

High-performance near-infrared imaging for breast cancer detection

[+] Author Affiliations
Yasser H. El-Sharkawy

Military Technical College, Department of Biomedical Engineering, Kobry Elkobbah, Cairo 11787, Egypt

Ashraf F. El-Sherif

Military Technical College, Department of Engineering Physics, Laser Photonics Research Group, Kobry Elkobbah, Cairo 11787, Egypt

CREOL, The College of Optics and Photonics, Building 53, 4000 Central Florida Boulevard, Orlando, Florida 32816

J. Biomed. Opt. 19(1), 016018 (Jan 27, 2014). doi:10.1117/1.JBO.19.1.016018
History: Received May 3, 2013; Revised December 17, 2013; Accepted December 30, 2013
Text Size: A A A

Abstract.  We present a method for the noninvasive determination of the size, position, and optical properties of tumors in the human breast. The tumor is first detected by photothermal imaging. It is then sized, located, and optically characterized using designed digital image processing and edge-detection pattern recognition. The method assumes that the tumor is spherical and inhomogeneous and embedded in an otherwise homogeneous tissue. Heat energy is deposited in the tissue by absorption of near-infrared (NIR) Nd:YAG laser radiation, and its subsequent conversion to heat via vibrational relaxation causes a rise in temperature of the tissue. The tumor absorbs and scatters NIR light more strongly than the surrounding healthy tissue. Heat will diffuse through the tissue, causing a rise in temperature of the surrounding tissue. Differentiation between normal and cancerous tissues is determined using IR thermal imaging. Results are presented on a 55-year-old patient with a papillary breast cancer. We found that these results provide the clinician with more detailed information about breast lesions detected by photothermal imaging and thereby enhance its potential for specificity.

Figures in this Article
© 2014 Society of Photo-Optical Instrumentation Engineers

Citation

Yasser H. El-Sharkawy and Ashraf F. El-Sherif
"High-performance near-infrared imaging for breast cancer detection", J. Biomed. Opt. 19(1), 016018 (Jan 27, 2014). ; http://dx.doi.org/10.1117/1.JBO.19.1.016018


Tables

Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

PubMed Articles
Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.