Special Section on Selected Topics in Biophotonics: Optical Coherence Tomography and Biomolecular Imaging with Coherent Raman Scattering Microscopy

Sources of errors in spatial frequency domain imaging of scattering media

[+] Author Affiliations
Nico Bodenschatz

Institut für Lasertechnologien in der Medizin und Meßtechnik, Helmholtzstr. 12, D-89081 Ulm, Germany

Arnd Brandes

Institut für Lasertechnologien in der Medizin und Meßtechnik, Helmholtzstr. 12, D-89081 Ulm, Germany

André Liemert

Institut für Lasertechnologien in der Medizin und Meßtechnik, Helmholtzstr. 12, D-89081 Ulm, Germany

Alwin Kienle

Institut für Lasertechnologien in der Medizin und Meßtechnik, Helmholtzstr. 12, D-89081 Ulm, Germany

J. Biomed. Opt. 19(7), 071405 (Jan 27, 2014). doi:10.1117/1.JBO.19.7.071405
History: Received September 30, 2013; Revised November 20, 2013; Accepted December 16, 2013
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Abstract.  Knowledge of the impact of potential sources of error in spatial frequency domain imaging (SFDI) is essential for the quantitative characterization of absorption and scattering in tissue and other turbid media. We theoretically investigate the error in the derived absorption and scattering parameter, subject to typical experimental and theoretical sources of errors. This provides a guideline to properly assess the significance of various parameters related to the measurement and the theoretical evaluation of spatial frequency domain reflectance data. At the same time, this study serves as a reference to estimate the overall precision of derived optical parameters of semi-infinite scattering media using SFDI.

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© 2014 Society of Photo-Optical Instrumentation Engineers

Citation

Nico Bodenschatz ; Arnd Brandes ; André Liemert and Alwin Kienle
"Sources of errors in spatial frequency domain imaging of scattering media", J. Biomed. Opt. 19(7), 071405 (Jan 27, 2014). ; http://dx.doi.org/10.1117/1.JBO.19.7.071405


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