Research Papers: Imaging

Catheter-based photoacoustic endoscope

[+] Author Affiliations
Joon-Mo Yang

Washington University in St. Louis, Department of Biomedical Engineering, Optical Imaging Laboratory, Campus Box 1097, One Brookings Drive, Street Louis, Missouri 63130

Chiye Li

Washington University in St. Louis, Department of Biomedical Engineering, Optical Imaging Laboratory, Campus Box 1097, One Brookings Drive, Street Louis, Missouri 63130

Ruimin Chen

University of Southern California, NIH Ultrasonic Transducer Resource Center, Department of Biomedical Engineering, 1042 Downey Way, University Park, Drive 130, Los Angeles, California 90089

Qifa Zhou

University of Southern California, NIH Ultrasonic Transducer Resource Center, Department of Biomedical Engineering, 1042 Downey Way, University Park, Drive 130, Los Angeles, California 90089

K. Kirk Shung

University of Southern California, NIH Ultrasonic Transducer Resource Center, Department of Biomedical Engineering, 1042 Downey Way, University Park, Drive 130, Los Angeles, California 90089

Lihong V. Wang

Washington University in St. Louis, Department of Biomedical Engineering, Optical Imaging Laboratory, Campus Box 1097, One Brookings Drive, Street Louis, Missouri 63130

J. Biomed. Opt. 19(6), 066001 (Jun 02, 2014). doi:10.1117/1.JBO.19.6.066001
History: Received January 20, 2014; Revised April 26, 2014; Accepted May 6, 2014
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Abstract.  We report a flexible shaft-based mechanical scanning photoacoustic endoscopy (PAE) system that can be potentially used for imaging the human gastrointestinal tract via the instrument channel of a clinical video endoscope. The development of such a catheter endoscope has been an important challenge to realize the technique’s benefits in clinical settings. We successfully implemented a prototype PAE system that has a 3.2-mm diameter and 2.5-m long catheter section. As the instrument’s flexible shaft and scanning tip are fully encapsulated in a plastic catheter, it easily fits within the 3.7-mm diameter instrument channel of a clinical video endoscope. Here, we demonstrate the intra-instrument channel workability and in vivo animal imaging capability of the PAE system.

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© 2014 Society of Photo-Optical Instrumentation Engineers

Citation

Joon-Mo Yang ; Chiye Li ; Ruimin Chen ; Qifa Zhou ; K. Kirk Shung, et al.
"Catheter-based photoacoustic endoscope", J. Biomed. Opt. 19(6), 066001 (Jun 02, 2014). ; http://dx.doi.org/10.1117/1.JBO.19.6.066001


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